{"id":9534,"date":"2025-09-16T22:00:51","date_gmt":"2025-09-16T15:00:51","guid":{"rendered":"https:\/\/huanqiuribao.com\/?p=9534"},"modified":"2025-09-16T11:43:00","modified_gmt":"2025-09-16T04:43:00","slug":"%e7%bb%b4%e7%94%9f%e7%b4%a0b3%e6%b2%bb%e7%96%97%e8%84%82%e8%82%aa%e8%82%9d","status":"publish","type":"post","link":"https:\/\/huanqiuribao.com\/?p=9534","title":{"rendered":"\u7ef4\u751f\u7d20B3\u6cbb\u7597\u8102\u80aa\u809d"},"content":{"rendered":"<p>\u7814\u7a76\u4eba\u5458\u53d1\u73b0microRNA-93\u662f\u8102\u80aa\u809d\u7684\u9057\u4f20\u9a71\u52a8\u56e0\u7d20\uff0c\u5e76\u8868\u660e\u7ef4\u751f\u7d20B3\u53ef\u4ee5\u6709\u6548\u6291\u5236\u8be5\u75be\u75c5\u3002<\/p>\n<p>\u5168\u7403\u7ea630%\u7684\u4eba\u53e3\u60a3\u6709\u4ee3\u8c22\u6027\u8102\u80aa\u809d\uff08MASLD\uff09\uff0c\u8fd9\u79cd\u75be\u75c5\u6b64\u524d\u7f3a\u4e4f\u9488\u5bf9\u6027\u7684\u6cbb\u7597\u65b9\u6cd5\u3002\u4e00\u9879\u7a81\u7834\u6027\u7684\u53d1\u73b0\uff0c\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u4e86\u4e00\u79cd\u52a0\u5267\u8be5\u75be\u75c5\u7684\u9057\u4f20\u56e0\u7d20\uff0c\u800c\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0cFDA\u6279\u51c6\u7684\u9488\u5bf9\u8be5\u56e0\u7d20\u6700\u6709\u6548\u7684\u836f\u7269\u6b63\u662f\u7ef4\u751f\u7d20B3\u3002<\/p>\n<p>\u97e9\u56fd\u851a\u5c71\u79d1\u5b66\u6280\u672f\u5927\u5b66\uff0c\u9996\u6b21\u663e\u793a\u4e86\u5728\u809d\u810f\u4e2d\u8868\u8fbe\u7684 microRNA-93 (miR-93) \u4f5c\u4e3a MASLD \u53d1\u5c55\u7684\u5173\u952e\u8c03\u8282\u56e0\u5b50\u7684\u4f5c\u7528\u3002miR-93\u662f\u7531\u4f53\u5185\u7684MIR93\u57fa\u56e0\u6240\u4ea7\u751f\u7684\u3002<\/p>\n<p>miR-93 \u662f\u4e00\u79cd\u5728\u809d\u7ec6\u80de\u4e2d\u8868\u8fbe\u7684\u7279\u6b8a RNA \u5206\u5b50\uff0c \u7814\u7a76\u56e2\u961f\u5728\u8102\u80aa\u809d\u60a3\u8005\u548c\u52a8\u7269\u6a21\u578b\u4e2d\u5747\u89c2\u5bdf\u5230 miR-93 \u6c34\u5e73\u5f02\u5e38\u5347\u9ad8\u3002\u901a\u8fc7\u5206\u5b50\u5206\u6790\uff0c\u4ed6\u4eec\u8bc1\u660e miR-93 \u901a\u8fc7\u6291\u5236 SIRT1\uff08\u4e00\u4e2a\u53c2\u4e0e\u809d\u7ec6\u80de\u8102\u8d28\u4ee3\u8c22\u7684\u57fa\u56e0\uff09\u7684\u8868\u8fbe\u6765\u4fc3\u8fdb\u8102\u8d28\u79ef\u805a\u3001\u708e\u75c7\u548c\u7ea4\u7ef4\u5316\u3002<\/p>\n<p>\u7528\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u53bb\u6389\u5c0f\u9f20\u4f53\u5185 miR-93\uff0c\u89c2\u5bdf\u5230\u809d\u810f\u8102\u80aa\u5806\u79ef\u663e\u8457\u51cf\u5c11\uff0c\u80f0\u5c9b\u7d20\u654f\u611f\u6027\u548c\u809d\u529f\u80fd\u6307\u6807\u4e5f\u663e\u8457\u6539\u5584\u3002\u589e\u52a0 miR-93 \u7684\u5c0f\u9f20\u5219\u8868\u73b0\u51fa\u809d\u810f\u4ee3\u8c22\u529f\u80fd\u6076\u5316\u3002<\/p>\n<p>\u6b64\u5916\uff0c\u5bf9150\u79cdFDA\u6279\u51c6\u836f\u7269\u7684\u7b5b\u67e5\u663e\u793a\uff0c\u70df\u9178\uff08\u7ef4\u751f\u7d20B3\uff09\u5bf9miR-93\u7684\u6291\u5236\u6700\u4e3a\u6709\u6548\u3002\u63a5\u53d7\u70df\u9178\u6cbb\u7597\u7684\u5c0f\u9f20\u809d\u810fmiR-93\u6c34\u5e73\u663e\u8457\u4e0b\u964d\uff0cSIRT1\u6d3b\u6027\u663e\u8457\u5347\u9ad8\u3002\u6fc0\u6d3b\u7684SIRT1\u4fee\u590d\u4e86\u88ab\u7834\u574f\u7684\u8102\u8d28\u4ee3\u8c22\u9014\u5f84\uff0c\u4ece\u800c\u4f7f\u809d\u810f\u8102\u8d28\u7a33\u6001\u6062\u590d\u6b63\u5e38\u3002<\/p>\n<p>\u7814\u7a76\u5c0f\u7ec4\u89e3\u91ca\u8bf4\uff1a\u201c\u8fd9\u9879\u7814\u7a76\u51c6\u786e\u5730\u9610\u660e\u4e86MASLD\u7684\u5206\u5b50\u8d77\u6e90\uff0c\u5e76\u8bc1\u660e\u4e86\u91cd\u65b0\u5229\u7528\u5df2\u83b7\u6279\u51c6\u7684\u7ef4\u751f\u7d20\u5316\u5408\u7269\u6765\u8c03\u8282\u8be5\u9014\u5f84\u7684\u6f5c\u529b\uff0c\u5177\u6709\u5f88\u9ad8\u7684\u8f6c\u5316\u4e34\u5e8a\u76f8\u5173\u6027\u3002\u201d<\/p>\n<p>\u4ed6\u4eec\u8865\u5145\u9053\uff0c\u201c\u9274\u4e8e\u70df\u9178\uff08\u7ef4\u751f\u7d20B3\uff09\u662f\u4e00\u79cd\u6210\u719f\u4e14\u5b89\u5168\u7684\u6cbb\u7597\u9ad8\u8102\u8840\u75c7\u7684\u836f\u7269\uff0c\u5b83\u6709\u671b\u6210\u4e3a\u9488\u5bf9 MASLD \u4e2d miR-93\u901a\u8def\u7684\u8054\u5408\u7597\u6cd5\u7684\u5019\u9009\u836f\u7269\u3002\u201d<\/p>\n<p>\u809d\u810f miR-93 \u901a\u8fc7\u6291\u5236 SIRT1 \u4fc3\u4f7f\u4ee3\u8c22\u529f\u80fd\u969c\u788d\u76f8\u5173\u8102\u80aa\u809d\u7684\u53d1\u75c5\u673a\u5236\u3002\u300a\u4ee3\u8c22\u300b\uff0c2025\uff1b169\uff1a156266 DOI\uff1a10.1016\/j.metabol.2025.156266\u3002\uff08\u5176\u4ed6\u6765\u6e90\uff09<\/p>\n<p>&nbsp;<\/p>\n<p>\u514d\u8d23\u58f0\u660e\uff1a\u7b2c\u4e09\u65b9\u65b0\u95fb\uff08\u6216\u56fe\u7247\uff09\u4e3a\u5206\u4eab\/\u63f4\u5f15\/\u50a8\u5b58\u4fe1\u606f\uff0c\u5176\u5185\u5bb9\u5e76\u4e0d\u4ee3\u8868\u672c\u62a5\/\u672c\u7f51\u7acb\u573a\uff0c\u5982\u6709\u9519\u8bef\u6216\u76f8\u5173\u4fb5\u6743\u8bf7\u8054\u7cfb\u6211\u4eec\u5220\u9664\uff0c\u8c22\u8c22\uff01<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u7814\u7a76\u4eba\u5458\u53d1\u73b0microRNA-93\u662f\u8102\u80aa\u809d\u7684\u9057\u4f20\u9a71\u52a8\u56e0\u7d20\uff0c\u5e76\u8868\u660e\u7ef4\u751f\u7d20B3\u53ef\u4ee5\u6709\u6548\u6291\u5236\u8be5\u75be\u75c5\u3002 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\u5206\u5b50\uff0c \u7814\u7a76\u56e2\u961f\u5728\u8102\u80aa\u809d\u60a3\u8005\u548c\u52a8\u7269\u6a21\u578b\u4e2d\u5747\u89c2\u5bdf\u5230 miR-93 \u6c34\u5e73\u5f02\u5e38\u5347\u9ad8\u3002\u901a\u8fc7\u5206\u5b50\u5206\u6790\uff0c\u4ed6\u4eec\u8bc1\u660e miR-93 \u901a\u8fc7\u6291\u5236 SIRT1\uff08\u4e00\u4e2a\u53c2\u4e0e\u809d\u7ec6\u80de\u8102\u8d28\u4ee3\u8c22\u7684\u57fa\u56e0\uff09\u7684\u8868\u8fbe\u6765\u4fc3\u8fdb\u8102\u8d28\u79ef\u805a\u3001\u708e\u75c7\u548c\u7ea4\u7ef4\u5316\u3002 \u7528\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u53bb\u6389\u5c0f\u9f20\u4f53\u5185 miR-93\uff0c\u89c2\u5bdf\u5230\u809d\u810f\u8102\u80aa\u5806\u79ef\u663e\u8457\u51cf\u5c11\uff0c\u80f0\u5c9b\u7d20\u654f\u611f\u6027\u548c\u809d\u529f\u80fd\u6307\u6807\u4e5f\u663e\u8457\u6539\u5584\u3002\u589e\u52a0 miR-93 \u7684\u5c0f\u9f20\u5219\u8868\u73b0\u51fa\u809d\u810f\u4ee3\u8c22\u529f\u80fd\u6076\u5316\u3002 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\u4ed6\u4eec\u8865\u5145\u9053\uff0c\u201c\u9274\u4e8e\u70df\u9178\uff08\u7ef4\u751f\u7d20B3\uff09\u662f\u4e00\u79cd\u6210\u719f\u4e14\u5b89\u5168\u7684\u6cbb\u7597\u9ad8\u8102\u8840\u75c7\u7684\u836f\u7269\uff0c\u5b83\u6709\u671b\u6210\u4e3a\u9488\u5bf9 MASLD \u4e2d miR-93\u901a\u8def\u7684\u8054\u5408\u7597\u6cd5\u7684\u5019\u9009\u836f\u7269\u3002\u201d \u809d\u810f miR-93 \u901a\u8fc7\u6291\u5236 SIRT1 \u4fc3\u4f7f\u4ee3\u8c22\u529f\u80fd\u969c\u788d\u76f8\u5173\u8102\u80aa\u809d\u7684\u53d1\u75c5\u673a\u5236\u3002\u300a\u4ee3\u8c22\u300b\uff0c2025\uff1b169\uff1a156266 DOI\uff1a10.1016\/j.metabol.2025.156266\u3002\uff08\u5176\u4ed6\u6765\u6e90\uff09 &nbsp; 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max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/huanqiuribao.com\/?p=9534\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u7ef4\u751f\u7d20B3\u6cbb\u7597\u8102\u80aa\u809d - Huanqiuribao\" \/>\n<meta property=\"og:description\" content=\"\u7814\u7a76\u4eba\u5458\u53d1\u73b0microRNA-93\u662f\u8102\u80aa\u809d\u7684\u9057\u4f20\u9a71\u52a8\u56e0\u7d20\uff0c\u5e76\u8868\u660e\u7ef4\u751f\u7d20B3\u53ef\u4ee5\u6709\u6548\u6291\u5236\u8be5\u75be\u75c5\u3002 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