{"id":26679,"date":"2026-03-11T10:30:03","date_gmt":"2026-03-11T03:30:03","guid":{"rendered":"https:\/\/huanqiuribao.com\/?p=26679"},"modified":"2026-03-11T12:57:35","modified_gmt":"2026-03-11T05:57:35","slug":"%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6%ef%bc%9a%e7%b3%96%e5%b0%bf%e7%97%85%e8%80%81%e8%8d%af%e7%ab%9f%e8%97%8f%e6%8a%97%e7%99%8c%e5%8a%9b","status":"publish","type":"post","link":"https:\/\/huanqiuribao.com\/?p=26679","title":{"rendered":"\u6700\u65b0\u7814\u7a76\uff1a\u7cd6\u5c3f\u75c5\u8001\u836f\u7adf\u85cf\u6297\u764c\u529b"},"content":{"rendered":"<p>\u6cbb\u7597\u7cd6\u5c3f\u75c5\u7684\u8001\u836f\u4e8c\u7532\u53cc\u80cd\uff08Metformin\uff09\uff0c\u53c8\u6709\u4eba\u79f0\u5b83\u4e3a\u5e93\u9c81\u5316\uff08Glucophage\uff09\u3001\u7f8e\u514b\u7cd6\uff08Metformin generics\uff09\u3001\u6216\u533b\u9662\u5e38\u5f00\u7684\u4e8c\u7532\u53cc\u80cd\u952d\u3002\u53f0\u5317\u8363\u603b\u9057\u4f20\u4f18\u751f\u79d1\u4e3b\u4efb\u5f20\u5bb6\u94ed\u8868\u793a\uff0c\u8fd1\u5341\u51e0\u5e74\u7684\u7814\u7a76\uff0c\u957f\u671f\u4f7f\u7528\u4e8c\u7532\u53cc\u80cd\u7684\u4eba\uff0c\u67d0\u4e9b\u764c\u75c7\u7684\u53d1\u751f\u7387\u6bd4\u8f83\u4f4e\u3002<\/p>\n<p>\u5f20\u5bb6\u94ed\u53d1\u6587\u5206\u4eab\uff0c\u539f\u6765\u8fd9\u9897\u836f\u8c03\u6574\u7684\u4e0d\u53ea\u662f\u8840\u7cd6\uff0c\u5b83\u5176\u5b9e\u5728\u6539\u53d8\u8eab\u4f53\u7684\u4ee3\u8c22\u73af\u5883\uff0c\u4e5f\u5728\u6162\u6162\u8c03\u6574\u7ec6\u80de\u6240\u5904\u7684\u5206\u5b50\u80cc\u666f\u3002\u4ed6\u5f62\u5bb9\uff0c\u5728\u7ec6\u80de\u91cc\uff0c\u6709\u4e00\u4e2a\u50cf\u7535\u529b\u8868\u4e00\u6837\u7684\u7cfb\u7edf\uff0c\u4f1a\u76d1\u6d4b\u80fd\u91cf\u72b6\u6001\uff0c\u8fd9\u4e2a\u7cfb\u7edf\u53eb\u505a\u5b89\u666e\u6d3b\u5316\u86cb\u767d\u6fc0\u9176\uff08AMPK, AMP activated protein kinase\uff09\u3002<\/p>\n<p>\u7814\u7a76\u8868\u660e\uff0c\u4e8c\u7532\u53cc\u80cd\u4f1a\u5f71\u54cd\u7ec6\u80de\u91cc\u7684\u53d1\u7535\u5382\uff0c\u4e5f\u5c31\u662f\u7c92\u7ebf\u4f53\uff0c\u5f53\u53d1\u7535\u5382\u7684\u8f93\u51fa\u7a0d\u5fae\u964d\u4f4e\u65f6\uff0c\u7ec6\u80de\u4f1a\u611f\u89c9\u5230\u80fd\u91cf\u53d8\u5c11\uff0c\u63a5\u7740\uff0c\u80fd\u91cf\u611f\u6d4b\u7cfb\u7edf\u5c31\u4f1a\u88ab\u542f\u52a8\uff0c\u7ec6\u80de\u91cc\u8d1f\u8d23\u751f\u957f\u7684\u8baf\u53f7\u4e5f\u4f1a\u6162\u6162\u964d\u4f4e\u3002<\/p>\n<p>\u764c\u75c7\u5f88\u591a\u65f6\u5019\u662f\u73af\u5883\u6162\u6162\u5f62\u6210\u7684\uff0c\u5f88\u591a\u4eba\u63d0\u5230\u764c\u75c7\uff0c\u7b2c\u4e00\u4e2a\u60f3\u5230\u7684\u662f\u57fa\u56e0\uff0c\u57fa\u56e0\u786e\u5b9e\u91cd\u8981\uff0c\u4f46\u73b0\u5728\u7684\u7814\u7a76\u8ba9\u6211\u4eec\u770b\u5230\u66f4\u5b8c\u6574\u7684\u753b\u9762\uff0c\u764c\u75c7\u5e38\u5e38\u662f\u5728\u4e00\u4e2a\u957f\u671f\u4e0d\u5e73\u8861\u7684\u5206\u5b50\u73af\u5883\u91cc\u6162\u6162\u5f62\u6210\u7684\u3002\u4f8b\u5982\u6162\u6027\u53d1\u708e\u3001\u80fd\u91cf\u5931\u8861\u3001\u514d\u75ab\u7cfb\u7edf\u75b2\u52b3\uff0c\u8fd9\u4e9b\u56e0\u7d20\u4f1a\u4e00\u70b9\u4e00\u70b9\u6539\u53d8\u7ec6\u80de\u7684\u884c\u4e3a\u3002<\/p>\n<p>\u6709\u5178\u578b\u73b0\u8c61\u53eb\u505a\u74e6\u4f2f\u683c\u6548\u5e94\uff08Warburg effect\uff09\uff0c\u764c\u7ec6\u80de\u4f1a\u7528\u4e00\u79cd\u6bd4\u8f83\u5feb\u7684\u65b9\u5f0f\u6765\u4ea7\u751f\u80fd\u91cf\uff0c\u6548\u7387\u4e0d\u4e00\u5b9a\u9ad8\uff0c\u4f46\u53ef\u4ee5\u5feb\u901f\u5236\u9020\u5f88\u591a\u5efa\u7b51\u6750\u6599\u3002\u800c\u4e8c\u7532\u53cc\u80cd\u4f1a\u8ba9\u80fd\u91cf\u4f9b\u5e94\u53d8\u5f97\u6bd4\u8f83\u8282\u5236\uff0c\u4e8e\u662f\u7ec6\u80de\u4f1a\u91cd\u65b0\u5b89\u6392\u8d44\u6e90\u3002\u80f0\u5c9b\u7d20\u5176\u5b9e\u4e5f\u662f\u4e00\u4e2a\u751f\u957f\u8baf\u53f7\uff0c\u5f53\u80f0\u5c9b\u7d20\u957f\u671f\u504f\u9ad8\u65f6\uff0c\u7ec6\u80de\u4f1a\u4e00\u76f4\u6536\u5230\u4e00\u4e2a\u4fe1\u606f\uff0c\u6301\u7eed\u5206\u88c2\u4e5f\u4f1a\u589e\u52a0\u5404\u79cd\u5408\u6210\u6d3b\u52a8\u3002<\/p>\n<p>\u800c\u4e8c\u7532\u53cc\u80cd\u7684\u4e00\u4e2a\u91cd\u8981\u4f5c\u7528\uff0c\u5c31\u662f\u8ba9\u80f0\u5c9b\u7d20\u4e0e\u76f8\u5173\u751f\u957f\u8baf\u53f7\u6162\u6162\u4e0b\u964d\u3002\u5f53\u8fd9\u4e9b\u8baf\u53f7\u51cf\u5c11\u65f6\uff0c\u6574\u4e2a\u8eab\u4f53\u7684\u5206\u5b50\u80cc\u666f\u4e5f\u4f1a\u6162\u6162\u6539\u53d8\u3002\u4f46\u764c\u7ec6\u80de\u5f88\u806a\u660e\uff0c\u5b83\u4eec\u4f1a\u5728\u8868\u9762\u653e\u4e0a\u4e00\u4e2a\u5206\u5b50\u7a0b\u5f0f\u6027\u6b7b\u4ea1\u914d\u4f53\u4e00\uff08PD-L1, Programmed death ligand one\uff09\u3002\u514d\u75ab\u7ec6\u80de\u770b\u5230\u5b83\uff0c\u5c31\u4f1a\u4ee5\u4e3a\u8fd9\u662f\u6b63\u5e38\u7ec6\u80de\uff0c\u4e8e\u662f\u653b\u51fb\u5c31\u505c\u6b62\u4e86\u3002<\/p>\n<p>\u7814\u7a76\u8bf4\u660e\uff0c\u4e8c\u7532\u53cc\u80cd\u53ef\u80fd\u4f1a\u5f71\u54cdPD-L1\u8fd9\u4e2a\u5206\u5b50\u7684\u7a33\u5b9a\u6027\uff0c\u540c\u65f6\u4e5f\u4f1a\u6539\u53d8\u80bf\u7624\u5468\u56f4\u7684\u514d\u75ab\u73af\u5883\u3002<\/p>\n<p>\u81ea\u7531\u65f6\u62a5<\/p>\n<p>&nbsp;<\/p>\n<p>\u514d\u8d23\u58f0\u660e\uff1a\u7b2c\u4e09\u65b9\u65b0\u95fb\uff08\u6216\u56fe\u7247\uff09\u4e3a\u5206\u4eab\/\u63f4\u5f15\/\u50a8\u5b58\u4fe1\u606f\uff0c\u5176\u5185\u5bb9\u5e76\u4e0d\u4ee3\u8868\u672c\u62a5\/\u672c\u7f51\u7acb\u573a\uff0c\u5982\u6709\u9519\u8bef\u6216\u76f8\u5173\u4fb5\u6743\u8bf7\u8054\u7cfb\u6211\u4eec\u5220\u9664\uff0c\u8c22\u8c22\uff01<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u6cbb\u7597\u7cd6\u5c3f\u75c5\u7684\u8001\u836f\u4e8c\u7532\u53cc\u80cd\uff08Metformin\uff09\uff0c\u53c8\u6709\u4eba\u79f0\u5b83\u4e3a\u5e93\u9c81\u5316\uff08Glucophage\uff09\u3001\u7f8e\u514b\u7cd6\uff08Metformin generics\uff09\u3001\u6216\u533b\u9662\u5e38\u5f00\u7684\u4e8c\u7532\u53cc\u80cd\u952d\u3002\u53f0\u5317\u8363\u603b\u9057\u4f20\u4f18\u751f\u79d1\u4e3b\u4efb\u5f20\u5bb6\u94ed\u8868\u793a\uff0c\u8fd1\u5341\u51e0\u5e74\u7684\u7814\u7a76\uff0c\u957f\u671f\u4f7f\u7528\u4e8c\u7532\u53cc\u80cd\u7684\u4eba\uff0c\u67d0\u4e9b\u764c\u75c7\u7684\u53d1\u751f\u7387\u6bd4\u8f83\u4f4e\u3002 \u5f20\u5bb6\u94ed\u53d1\u6587\u5206\u4eab\uff0c\u539f\u6765\u8fd9\u9897\u836f\u8c03\u6574\u7684\u4e0d\u53ea\u662f\u8840\u7cd6\uff0c\u5b83\u5176\u5b9e\u5728\u6539\u53d8\u8eab\u4f53\u7684\u4ee3\u8c22\u73af\u5883\uff0c\u4e5f\u5728\u6162\u6162\u8c03\u6574\u7ec6\u80de\u6240\u5904\u7684\u5206\u5b50\u80cc\u666f\u3002\u4ed6\u5f62\u5bb9\uff0c\u5728\u7ec6\u80de\u91cc\uff0c\u6709\u4e00\u4e2a\u50cf\u7535\u529b\u8868\u4e00\u6837\u7684\u7cfb\u7edf\uff0c\u4f1a\u76d1\u6d4b\u80fd\u91cf\u72b6\u6001\uff0c\u8fd9\u4e2a\u7cfb\u7edf\u53eb\u505a\u5b89\u666e\u6d3b\u5316\u86cb\u767d\u6fc0\u9176\uff08AMPK, AMP activated protein kinase\uff09\u3002 \u7814\u7a76\u8868\u660e\uff0c\u4e8c\u7532\u53cc\u80cd\u4f1a\u5f71\u54cd\u7ec6\u80de\u91cc\u7684\u53d1\u7535\u5382\uff0c\u4e5f\u5c31\u662f\u7c92\u7ebf\u4f53\uff0c\u5f53\u53d1\u7535\u5382\u7684\u8f93\u51fa\u7a0d\u5fae\u964d\u4f4e\u65f6\uff0c\u7ec6\u80de\u4f1a\u611f\u89c9\u5230\u80fd\u91cf\u53d8\u5c11\uff0c\u63a5\u7740\uff0c\u80fd\u91cf\u611f\u6d4b\u7cfb\u7edf\u5c31\u4f1a\u88ab\u542f\u52a8\uff0c\u7ec6\u80de\u91cc\u8d1f\u8d23\u751f\u957f\u7684\u8baf\u53f7\u4e5f\u4f1a\u6162\u6162\u964d\u4f4e\u3002 \u764c\u75c7\u5f88\u591a\u65f6\u5019\u662f\u73af\u5883\u6162\u6162\u5f62\u6210\u7684\uff0c\u5f88\u591a\u4eba\u63d0\u5230\u764c\u75c7\uff0c\u7b2c\u4e00\u4e2a\u60f3\u5230\u7684\u662f\u57fa\u56e0\uff0c\u57fa\u56e0\u786e\u5b9e\u91cd\u8981\uff0c\u4f46\u73b0\u5728\u7684\u7814\u7a76\u8ba9\u6211\u4eec\u770b\u5230\u66f4\u5b8c\u6574\u7684\u753b\u9762\uff0c\u764c\u75c7\u5e38\u5e38\u662f\u5728\u4e00\u4e2a\u957f\u671f\u4e0d\u5e73\u8861\u7684\u5206\u5b50\u73af\u5883\u91cc\u6162\u6162\u5f62\u6210\u7684\u3002\u4f8b\u5982\u6162\u6027\u53d1\u708e\u3001\u80fd\u91cf\u5931\u8861\u3001\u514d\u75ab\u7cfb\u7edf\u75b2\u52b3\uff0c\u8fd9\u4e9b\u56e0\u7d20\u4f1a\u4e00\u70b9\u4e00\u70b9\u6539\u53d8\u7ec6\u80de\u7684\u884c\u4e3a\u3002 \u6709\u5178\u578b\u73b0\u8c61\u53eb\u505a\u74e6\u4f2f\u683c\u6548\u5e94\uff08Warburg effect\uff09\uff0c\u764c\u7ec6\u80de\u4f1a\u7528\u4e00\u79cd\u6bd4\u8f83\u5feb\u7684\u65b9\u5f0f\u6765\u4ea7\u751f\u80fd\u91cf\uff0c\u6548\u7387\u4e0d\u4e00\u5b9a\u9ad8\uff0c\u4f46\u53ef\u4ee5\u5feb\u901f\u5236\u9020\u5f88\u591a\u5efa\u7b51\u6750\u6599\u3002\u800c\u4e8c\u7532\u53cc\u80cd\u4f1a\u8ba9\u80fd\u91cf\u4f9b\u5e94\u53d8\u5f97\u6bd4\u8f83\u8282\u5236\uff0c\u4e8e\u662f\u7ec6\u80de\u4f1a\u91cd\u65b0\u5b89\u6392\u8d44\u6e90\u3002\u80f0\u5c9b\u7d20\u5176\u5b9e\u4e5f\u662f\u4e00\u4e2a\u751f\u957f\u8baf\u53f7\uff0c\u5f53\u80f0\u5c9b\u7d20\u957f\u671f\u504f\u9ad8\u65f6\uff0c\u7ec6\u80de\u4f1a\u4e00\u76f4\u6536\u5230\u4e00\u4e2a\u4fe1\u606f\uff0c\u6301\u7eed\u5206\u88c2\u4e5f\u4f1a\u589e\u52a0\u5404\u79cd\u5408\u6210\u6d3b\u52a8\u3002 \u800c\u4e8c\u7532\u53cc\u80cd\u7684\u4e00\u4e2a\u91cd\u8981\u4f5c\u7528\uff0c\u5c31\u662f\u8ba9\u80f0\u5c9b\u7d20\u4e0e\u76f8\u5173\u751f\u957f\u8baf\u53f7\u6162\u6162\u4e0b\u964d\u3002\u5f53\u8fd9\u4e9b\u8baf\u53f7\u51cf\u5c11\u65f6\uff0c\u6574\u4e2a\u8eab\u4f53\u7684\u5206\u5b50\u80cc\u666f\u4e5f\u4f1a\u6162\u6162\u6539\u53d8\u3002\u4f46\u764c\u7ec6\u80de\u5f88\u806a\u660e\uff0c\u5b83\u4eec\u4f1a\u5728\u8868\u9762\u653e\u4e0a\u4e00\u4e2a\u5206\u5b50\u7a0b\u5f0f\u6027\u6b7b\u4ea1\u914d\u4f53\u4e00\uff08PD-L1, Programmed death ligand one\uff09\u3002\u514d\u75ab\u7ec6\u80de\u770b\u5230\u5b83\uff0c\u5c31\u4f1a\u4ee5\u4e3a\u8fd9\u662f\u6b63\u5e38\u7ec6\u80de\uff0c\u4e8e\u662f\u653b\u51fb\u5c31\u505c\u6b62\u4e86\u3002 \u7814\u7a76\u8bf4\u660e\uff0c\u4e8c\u7532\u53cc\u80cd\u53ef\u80fd\u4f1a\u5f71\u54cdPD-L1\u8fd9\u4e2a\u5206\u5b50\u7684\u7a33\u5b9a\u6027\uff0c\u540c\u65f6\u4e5f\u4f1a\u6539\u53d8\u80bf\u7624\u5468\u56f4\u7684\u514d\u75ab\u73af\u5883\u3002 \u81ea\u7531\u65f6\u62a5 &nbsp; 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content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/huanqiuribao.com\/?p=26679\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u6700\u65b0\u7814\u7a76\uff1a\u7cd6\u5c3f\u75c5\u8001\u836f\u7adf\u85cf\u6297\u764c\u529b - Huanqiuribao\" \/>\n<meta property=\"og:description\" content=\"\u6cbb\u7597\u7cd6\u5c3f\u75c5\u7684\u8001\u836f\u4e8c\u7532\u53cc\u80cd\uff08Metformin\uff09\uff0c\u53c8\u6709\u4eba\u79f0\u5b83\u4e3a\u5e93\u9c81\u5316\uff08Glucophage\uff09\u3001\u7f8e\u514b\u7cd6\uff08Metformin 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